Recent decisions of the US Courts have had a significant impact on the prospects for obtaining useful protection for life sciences inventions in the US. Indeed the ever changing status of US patent law represents constant challenge to companies in the life sciences industry. The recent call by the UK BioIndustry Association for the US Supreme Court to review the latest controversial decision therefore comes as a welcome intervention and suggests that the industry intends to fight this issue head on. Whilst we will need to continue to adapt to the law as it changes, it seems that we shouldn't give up hope just yet!